Hereditary Cancer Testing was designed to educate lay professional audiences with no genetics background about implementing hereditary cancer testing in the clinic. This course is for:
- Physicians, nurses and other health care providers in family/internal medicine and oncology
- Leaders in hospitals and healthcare systems
- Research and development teams in pharmaceuticals and biotechnology
- Business and sales professionals in the molecular diagnostics space and areas that support this space
- Health IT companies developing tools to manage genetic information
- Insurance companies who want to understand how to value hereditary cancer tests
Learn how to implement and scale hereditary cancer testing across your practice
Giving patients the best care possible means knowing about the latest tools and technologies for diagnosing and treating disease and being able to evaluate and use them in practice. Our course covers the following topics:
Taking a cancer family history
Many providers struggle capturing an accurate cancer family history. Learn about what key features to look for, common misconceptions and tools for having your patients collect their own family history.
Who should have cancer genetic testing
Hereditary breast/ovarian cancer and Lynch syndrome (colorectal) are two of the most common, actionable cancer syndromes where excellent genetic tests are available. Learn to recognize patients in your practice who might benefit from genetic testing for hereditary cancers.
Cancer genetic case studies
What are some of the more common scenarios where genetic testing is used? We’ll discuss common cases that you’re likely to encounter in your practice.
Managing patients undergoing genetic testing
What are the best sources of information for managing my patients through the genetic testing process? What is the role of a genetic counselor and how do I find one?
Clinical validity of hereditary cancer tests
Most people assume that larger gene panels are better than smaller ones, but not all genes on large hereditary cancer testing panels are backed by strong evidence of association with disease. Moreover, some genes are not as predictive as others. Learn about the clinical validity of different cancer genes found on popular gene panel tests.
Analytical validity of genetic tests
Next-gen sequencing (NGS) is used by most labs for hereditary cancer gene testing, but NGS doesn’t detect all relevant variants. Learn why it’s important to consider the laboratory analysis method when evaluating genetic tests.
Assessing the pathogenicity of variants
Not all variants in disease genes are pathogenic, or disease-causing. Learn how most labs interpret variants for pathogenicity and why variants of uncertain significance are so undesirable.
Scope and selection of hereditary cancer tests
Dozens of labs offer dozens of hereditary cancer testing products. Why are there so many and what is the difference? How do you select the test that’s right for your patient?
Interpreting genetic test reports
There are some common misinterpretations of genetic test results that can actually harm your patient. Learn to interpret genetic test results correctly and avoid putting your patient at risk.
Selecting a genetic testing lab
Dozens of labs offer genetic testing, so choosing a lab can be a daunting task. Learn what considerations go into selecting a testing laboratory and who are some of the labs currently offering cancer genetic testing.
About the course
Hereditary Cancer Testing consists of the following:
- An introduction plus ten short didactic videos (total watch time ~1 hour) available to watch on-demand
- Optional hands-on exercises (~30 min)
- An active discussion forum
- A community of like-minded professionals with opportunities for ongoing engagement
Please note: We recommend that students taking the Hereditary Cancer Testing course have a basic understanding of human genetics before enrolling. If you don’t have a background in genetics – or if you want a quick refresher - we offer two free online courses to bring you up to speed: PM101: Human Genomics (~30 min) and PM102: Genes, Heredity and Disease (~40 min).
The information provided through this course is for educational purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition.
All materials are copyrighted. Republication or redistribution of PMA content is prohibited without prior written consent. PMA shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.
Tell us about yourself
Hereditary Cancer Testing - Introduction (7:05)
Taking a Cancer Family History (5:04)
Who Should Have Cancer Genetic Testing (6:38)
Cancer Genetic Case Studies (4:06)
Managing Patients Who Have Genetic Testing (3:13)
Clinical Validity of Hereditary Cancer Tests (6:00)
Analytical Validity of Genetic Tests (5:03)
Assessing the Pathogenicity of Variants (7:19)
Scope and Selection of Hereditary Cancer Tests (5:53)
Interpreting Genetic Test Reports (3:54)
Selecting a Genetic Testing Laboratory (5:22)
Phosphorus sample test report (positive cancer)
Myriad sample test report (BRCA1 positive)
Invitae sample test report (positive cancer)
Color sample test report (positive cancer)
Ambry sample test report (BRCA 2 positive)
I thank the creators and organizers for this excellent course
I thank the creators and organizers for this excellent courseRead Less
I thoroughly enjoyed taking this course. I already order testing regularly, and It was interesting to know that it might not be a smart idea to order the fu...Read More
I thoroughly enjoyed taking this course. I already order testing regularly, and It was interesting to know that it might not be a smart idea to order the full customNext Cancer panel from Ambry, or the Multi Cancer Panel from Invitae. I was always thinking anything they do find is good information for the patient and their family even if we don't have all of the answers now. Most insurance covers for our patients so we typically order 80 genes on all patients. Thank you for offering this. I have recommended about 10 of our volunteers who are aspiring genetic counselors to take this test. :-) Kindest Regards, KimRead Less
It is a really helpful course. Wonderful explanations, adequate amount of information for non geneticists willing to implement genetic cancer testing in thei...Read More
It is a really helpful course. Wonderful explanations, adequate amount of information for non geneticists willing to implement genetic cancer testing in their practice. Thank you very much!Read Less
Excellent! The material was very easy to follow and understand, just what clinicians need to know.
Excellent! The material was very easy to follow and understand, just what clinicians need to know.Read Less
Outstanding and to the point!
Outstanding and to the point!Read Less
Very well spoken and presented. However, several typos and misspelled words early in the presentation.
Very well spoken and presented. However, several typos and misspelled words early in the presentation.Read Less
Great and interested topic. presented well.
Great and interested topic. presented well.Read Less
The presentation provided relevant information. I appreciated the content discussed. However, there were slides that had glitches. The glitches were severe e...Read More
The presentation provided relevant information. I appreciated the content discussed. However, there were slides that had glitches. The glitches were severe enough that I had to refresh the pages several different times.Read Less