This is the second course in the Essential Precision Medicine core series that explores the field of genomic and precision medicine. These courses are meant for a lay person (i.e. non-geneticist) who wishes to gain some basic genomic literacy and an understanding of the foundational concepts and vocabulary used in genomic and precision medicine.
What you'll learn
In this brief course (total run time ~40 min) we'll explore the genetic basis of diseases. We’ll focus on two main types of genetic diseases: Classical rare Mendelian (monogenic) diseases and common (polygenic) diseases. We’ll explore characteristics of both types of genetic diseases, break down GWAS studies, and touch on newer polygenic risk scores.
Our courses aim to minimize the jargon and teach precisely what is needed, and not more. If you're looking for a deep understanding of genetics, this isn't the course for you. If you want to be conversational in genomics, are currently working in a field that touches on precision medicine, ready to implement genetic testing in your medical practice, or simply want to understand the value and limits of available genetic tests, you're in the right place!
After taking this course, you should be able to do the following:
- Distinguish features of monogenic vs polygenic diseases
- Understand how GWAS work
- Discern the different information provided by p values and odds ratios
- Appreciate the value and limitations of polygenic risk scores
Welcome to Genes, Heredity and Disease
Genes, Heredity and Disease: Introduction
Mendelian (monogenic) diseases (12:58)
Recognizing a mendelian disease/trait (5:17)
Multifactorial (polygenic) diseases (11:26)
Strength of genetic associations (12:34)
Again, excellent presentation of slides and material. Discussion of comparison of Mendelian vs Multifactorial Dx, genetic association, odds ratio and more.
Again, excellent presentation of slides and material. Discussion of comparison of Mendelian vs Multifactorial Dx, genetic association, odds ratio and more.Read Less
Super course that bundles complex theory into clear segments
Super course that bundles complex theory into clear segmentsRead Less
This course was straight-forward and gave a concise review of statistical significance vs. clinical significance.
This course was straight-forward and gave a concise review of statistical significance vs. clinical significance.Read Less
give me clear picture about basic of clinical genetic in short time
give me clear picture about basic of clinical genetic in short timeRead Less
educational material.Read Less
I want to congratulate the creators and organizers of the course
I want to congratulate the creators and organizers of the courseRead Less